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Specifically, GLP-1RAs reduce SREBP-2 expression via activation of the SIRT6-AMPK pathway, resulting in decreased expression of cholesterol and bile acid synthesis genes, and increased expression of genes associated with RCT and LDL-C uptake

This resulted in differing numbers of patients influencing either end of the KaplanMeier survival curves and the possibility that the behavior of the patients at the beginning of the analysis may have differed from that of the patients nearer the end of the analysis

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The frequently used up-conversion materials display excellent stability against the photochemical degradation [156], which photoconverts by hydrophobic to hydrophilic conversions, by changing the effective surface charges, or by changing conformations